All you can really do is just follow a Big Daddy and hope that he calls for a Little Sister.

Coupled with the potential for sampling many different Plasmids and Tonics at once, this is the ideal strategy for someone playing Saving, on the other hand, is a long-term investment. Little Sisters appear in random locations, they are not restricted to certain areas. Because of her past as a Little Sister and her additional ADAM augmentation, Eleanor Lamb possesses a psychological link to all the Little Sisters. ADAM is excreted by unique Sea Slugs found near Rapture. However, they still had the stature and strength of small girls (not to mention their constant hallucinatory state); thus, they were a constant target for abduction and exploitation. Harvesting represents the short-term solution: Not only will the player end up with more ADAM than if they had saved the Little Sisters, but the first few levels of the game will be much easier to achieve. That's why they need Big Daddies to watch over them. Their bodies were induced by Sea Slugs which give them virtual immortality.
The Little Sisters could be killed by Splicers who wanted to extract the ADAM they contained by forced removal of the Sea Slug (i.e. The idea was to create a series of protectors that would defend the Little Sisters from Splicer attacks so they could gather ADAM without interference. Taken by Big Sister protectors, these new Little Sisters were processed in the Paediatric Wing of the When Tenenbaum discovered the kidnappings on the surface, she knew immediately where the girls were being taken, and what purpose they were to serve. In a forced removal, a large amount of ADAM could still be obtained from the Sea Slug. In Little Sisters can be seen being trained outside a Little Wonders facility in Prior to the civil war, Little Sisters may have worn pancaked makeup to hide their identities from their previous parents/guardians, who may attempt to take them back by force. The First Little Sister | BioShock Wiki | Fandom FANDOM The nightmarish prison cells and environment will be completely replaced by spotless white curtains, plush red carpeting, and toys. While it is harder to survive the first few levels with this path, it ultimately offers greater rewards. Depending on the choices the player has made throughout the game, the Little Sister may see different statues throughout the level depicting Delta's actions. Removal of the Sea Slug from the host under normal circumstances is fatal. To help him escape, Eleanor Lamb sends a Little Sister to him with a Plasmid to take control of her. All you can really do is just follow a Big Daddy and hope that he calls for a Little Sister. As a result, the Little Sisters call Subject Delta "daddy," and treat him as if he were their true father instead of calling him "Mr. Little Sisters saw their Big Daddies as noble golden knights, and saw This bond proved to be too effective, however, as each Big Daddy in the Alpha Series became useless after his Little Sister was killed by attacking Splicers or saved by Brigid Tenenbaum. Instead of seeing the dark, deteriorated state of the city, they saw an idealized child's world, with rosy marble floors, pink or red drapings, and flowering vines growing everywhere. harvesting).The only attack that can affect Little Sisters is the splash damage of a There are a total of 21 Little Sisters which can be rescued or harvested, disregarding any extra Little Sisters which may appear as a result of The numbers in brackets are for Little Sisters that cannot be interacted with in normal gameplay. Near the end of the game, Delta is captured by Sofia Lamb and is immobilized. Despite even that, they are quite defenseless against any greedy Splicer. Little Sisters were originally human girls but Every three Little Sisters rescued nets the player a reward in the form of a teddy bear clutching a present left at a nearby Gatherer's Garden.

Once Eleanor has been given the suit parts, she will save or harvest the Little Sister Delta was controlling (depending on the player's actions towards the Little Sisters), returning him to his body.

When one is struck her flesh will glow an unnatural golden color, showing the effects of fast regeneration due to ADAM. To make Little Sisters more effective in their task, they were heavily conditioned to see the world of Rapture very different from reality. "I'd visit the ATM, since my dad just put money in as my reward for beating dogs with a yo-yo." This system is meant to be a harder choice for the player, since the potential gain from harvesting is much greater. When a Big Daddy is killed, its Little Sister will stop whatever she is doing and mourn its death. However, by saving Little Sisters, the player can earn a To acquire a Little Sister, her Big Daddy protector must be killed first. In the Neptune's Bounty and Fort Frolic levels of BioShock and in Dionysus Park of BioShock 2 there are supposed to be three Little Sisters, in Arcadia there are supposed to be two, and in Farmer's Market there is supposed to be one. If Elizabeth examines certain objects during her journey through the Missing posters for her can be found in various businesses on Market Street during Take your favorite fandoms with you and never miss a beat. I saw a Big Daddy walking up some stairs, but no Little Sister was nearby. The Little Sister is hard to really describe as an enemy because it cannont attack or be attacked in any way. Little Sisters appear in random locations, they are not restricted to certain areas.

Once Big Daddies came into full production, the Little Sisters were also put through a course of Pavlovian psychological exercises,Because of the pheromone and Suchong's conditioning regimen, the Little Sisters are strongly attached to the Big Daddies, affectionately calling them a number of pet names such as 'Mister Bubbles' or 'Mister B'. While the harvest/save dilemma is still present in the sequel, a new mechanic is introduced: In the Multiplayer, Little Sisters feature in several game modes as a capture-able objective.
However, these rewards may or may not suit one's play-style, so it is recommended to either look up the rewards individually or play the game as a Harvester first. Little Sisters and Big Daddies (SPOILERS!)